Construct · 1 fields · 1 citations

differential scanning fluorimetry melting temperature: a standalone construct

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Biopharmaceutical development

midpoint unfolding temperature read from dye fluorescence during heating, used to rank formulations and ligands.

In biopharmaceutical development, differential scanning fluorimetry melting temperature refers to midpoint unfolding temperature read from dye fluorescence during heating, used to rank formulations and ligands. This meaning comes from Niesen (2007) in Nature Protocols.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cellular thermal shift assay1 fields · 1 citationsanchor · a standalone construct development1 fields · 2 citationsanchor · a standalone construct rank4 fields · 8 citationsjingle · one word, four constructs

References

Niesen, F. H., Berglund, H., & Vedadi, M. (2007). The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability. Nature Protocols, 2(9), 2212-2221. https://doi.org/10.1038/nprot.2007.321

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