Construct · 1 fields · 1 citations

dispersion model of hepatic elimination: a standalone construct

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Pharmacokinetics

a model of liver clearance in which drug spreads axially as it flows through the sinusoids, lying between the well-stirred and parallel-tube models.

In pharmacokinetics, dispersion model of hepatic elimination refers to a model of liver clearance in which drug spreads axially as it flows through the sinusoids, lying between the well-stirred and parallel-tube models. This meaning comes from Roberts (1986) in Journal of Pharmacokinetics and Biopharmaceutics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

clearance1 fields · 2 citationsanchor · a standalone construct dispersion4 fields · 6 citationsjingle · one word, four constructs elimination4 fields · 7 citationsjingle · one word, four constructs

References

Roberts, M. S., & Rowland, M. (1986). A dispersion model of hepatic elimination: 1. Formulation of the model and bolus considerations. Journal of Pharmacokinetics and Biopharmaceutics, 14(3), 227-260. https://doi.org/10.1007/bf01106706

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