Construct · 1 fields · 1 citations

DPYD gene activity score: a standalone construct

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Pharmacogenomics

a score summing the function of a person's two DPYD alleles to predict enzyme activity and fluoropyrimidine dose needs.

In pharmacogenomics, DPYD gene activity score refers to a score summing the function of a person's two DPYD alleles to predict enzyme activity and fluoropyrimidine dose needs. This meaning comes from Henricks (2015) in Pharmacogenomics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

dose3 fields · 3 citationsinvariant · one construct, three systems function5 fields · 6 citationsjingle · one word, five constructs person3 fields · 6 citationsjingle · one word, three constructs

References

Henricks, L. M., Lunenburg, C. A., Meulendijks, D., Gelderblom, H., Cats, A., Swen, J. J., Schellens, J. H., & Guchelaar, H. (2015). Translating DPYD Genotype into DPD Phenotype: Using the DPYD Gene Activity Score. Pharmacogenomics, 16(11), 1275-1284. https://doi.org/10.2217/pgs.15.70

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