Construct · 1 fields · 1 citations

epigenome editing: a standalone construct

One name. One construct. A landmark on the map.

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Genome editing

changing a gene's activity by delivering a chromatin-modifying enzyme to its promoter or enhancer, leaving DNA intact.

In genome editing, epigenome editing refers to changing a gene's activity by delivering a chromatin-modifying enzyme to its promoter or enhancer, leaving DNA intact. This meaning comes from Hilton (2015) in Nature Biotechnology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

editing1 fields · 2 citationsanchor · a standalone construct enhancer1 fields · 1 citationsanchor · a standalone construct promoter1 fields · 1 citationsanchor · a standalone construct

References

Hilton, I. B., D'Ippolito, A. M., Vockley, C. M., Thakore, P. I., Crawford, G. E., Reddy, T. E., & Gersbach, C. A. (2015). Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nature Biotechnology, 33(5), 510-517. https://doi.org/10.1038/nbt.3199

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