Construct · 1 fields · 1 citations

genetic background effect: a standalone construct

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Genetics

the way the rest of the genome changes the observed effect of a given mutation, so the same mutation looks different across strains or people.

In genetics, genetic background effect refers to the way the rest of the genome changes the observed effect of a given mutation, so the same mutation looks different across strains or people. This meaning comes from Chandler (2013) in Trends in Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

mutation4 fields · 4 citationsjingle · one word, four constructs rest1 fields · 1 citationsanchor · a standalone construct

References

Chandler, C. H., Chari, S., & Dworkin, I. (2013). Does your gene need a background check? How genetic background impacts the analysis of mutations, genes, and evolution. Trends in Genetics, 29(6), 358-366. https://doi.org/10.1016/j.tig.2013.01.009

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