Construct · 1 fields · 1 citations

genetic compensation: a standalone construct

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Genetics

the upregulation of related genes after a harmful mutation, which hides the expected defect in mutants but not after gene knockdown.

In genetics, genetic compensation refers to the upregulation of related genes after a harmful mutation, which hides the expected defect in mutants but not after gene knockdown. This meaning comes from Rossi (2015) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

compensation2 fields · 2 citationsjingle · one word, two constructs defect4 fields · 7 citationsjingle · one word, four constructs knockdown2 fields · 2 citationsjingle · one word, two constructs

References

Rossi, A., Kontarakis, Z., Gerri, C., Nolte, H., Hölper, S., Krüger, M., & Stainier, D. Y. R. (2015). Genetic compensation induced by deleterious mutations but not gene knockdowns. Nature, 524(7564), 230-233. https://doi.org/10.1038/nature14580

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