Construct · 1 fields · 1 citations

Haldane's indirect method: a standalone construct

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Human genetics

estimation of a human mutation rate from disease frequency and reduced fitness, assuming new mutations balance those lost by selection.

In human genetics, Haldane's indirect method refers to estimation of a human mutation rate from disease frequency and reduced fitness, assuming new mutations balance those lost by selection. This meaning comes from Haldane (1935) in Journal of Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

balance4 fields · 5 citationsjingle · one word, four constructs estimation3 fields · 3 citationsjingle · one word, three constructs fitness4 fields · 5 citationsjingle · one word, four constructs

References

Haldane, J. B. S. (1935). The rate of spontaneous mutation of a human gene. Journal of Genetics, 31(3), 317-326. https://doi.org/10.1007/bf02982403

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