Construct · 1 fields · 1 citations

insulated neighborhood: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
insulatedneighborhood1 CONSTRUCTInsulated neighborhoodDOWEN · GENOME ORGANISATION

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Genome organisation

a chromatin loop anchored by bound insulator protein that holds an enhancer and its target gene together and shuts out others.

In genome organisation, insulated neighborhood refers to a chromatin loop anchored by bound insulator protein that holds an enhancer and its target gene together and shuts out others. This meaning comes from Dowen (2014) in Cell.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructsenhancer1 fields · 1 citationsanchor · a standalone constructinsulator2 fields · 2 citationsjingle · one word, two constructs

References

  1. Dowen, J. M., Fan, Z. P., Hnisz, D., Ren, G., Abraham, B. J., Zhang, L. N., Weintraub, A. S., Schuijers, J., Lee, T. I., Zhao, K., & Young, R. A. (2014). Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes. Cell, 159(2), 374-387. https://doi.org/10.1016/j.cell.2014.09.030

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