Construct · 1 fields · 1 citations

iron-responsive element: a standalone construct

One name. One construct. A landmark on the map.

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iron-responsiveelement1 CONSTRUCTIron-responsive elementHENTZE · RNA BIOLOGY

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RNA biology

a stem-loop in a transcript bound by a regulatory protein when iron is scarce, controlling its translation or stability.

In RNA biology, iron-responsive element refers to a stem-loop in a transcript bound by a regulatory protein when iron is scarce, controlling its translation or stability. This meaning comes from Hentze (1987) in Science.[1]

Unit
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Measured by

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Nearby constructs

element3 fields · 5 citationsjingle · one word, three constructsstability4 fields · 5 citationsjingle · one word, four constructstranscript2 fields · 4 citationsjingle · one word, two constructs

References

  1. Hentze, M. W., Caughman, S. W., Rouault, T. A., Barriocanal, J. G., Dancis, A., Harford, J. B., & Klausner, R. D. (1987). Identification of the Iron-Responsive Element for the Translational Regulation of Human Ferritin mRNA. Science, 238(4833), 1570-1573. https://doi.org/10.1126/science.3685996

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