Construct · 1 fields · 1 citations

lesion: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaningblightcompare the meanings
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lesion1 CONSTRUCTLesion methodRORDEN · LESION METHOD

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Behavioural neuroscience

The brain lesion method

In behavioural neuroscience the lesion method is a research technique rather than the tissue itself: a specific brain region is deliberately damaged, or a naturally occurring injury is studied, and the function of that region is inferred from the deficits that appear once it stops working. The approach runs from Broca's nineteenth-century aphasia cases to modern imaging, and Rorden and Karnath's 2004 Using human brain lesions to infer function reviewed its logic and its standing beside functional imaging. Here the word names a way of reasoning about which part of the brain does what, so the referent is an inferential method built on damage, not the clinical patch of injured tissue it exploits, and not a diseased spot on a plant.[1]

Unit
A study relating damage in one brain region to the deficits that follow
Recovery means
Not applicable
Measured by
Function is inferred by mapping the site and extent of damage against measured behavioural deficits

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Nearby constructs

attention5 fields · 10 citationsjingle · one name, five constructsbody2 fields · 3 citationsjingle · one word, two constructs

References

  1. Rorden, C., & Karnath, H. O. (2004). Using human brain lesions to infer function: A relic from a past era in the fMRI age? Nature Reviews Neuroscience, 5(10), 812–819. https://doi.org/10.1038/nrn1521

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