Construct · 1 fields · 1 citations

ligand efficiency-dependent lipophilicity: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

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Drug discovery

ratio of lipophilicity to ligand efficiency, flagging compounds that gain potency through excess lipophilicity.

In drug discovery, ligand efficiency-dependent lipophilicity refers to ratio of lipophilicity to ligand efficiency, flagging compounds that gain potency through excess lipophilicity. This meaning comes from Keserü (2009) in Nature Reviews Drug Discovery.[1]

Unit
Recovery means
Measured by

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Nearby constructs

efficiency4 fields · 5 citationsjingle · one word, four constructs gain4 fields · 4 citationsjingle · one word, four constructs ligand efficiency1 fields · 1 citationsanchor · a standalone construct

References

Keserü, G. M., & Makara, G. M. (2009). The influence of lead discovery strategies on the properties of drug candidates. Nature Reviews Drug Discovery, 8(3), 203-212. https://doi.org/10.1038/nrd2796

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