Construct · 1 fields · 1 citations

lineage addiction: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Oncology

the dependence of a tumor on master regulators of the normal tissue lineage it arose from, which act as survival oncogenes when amplified.

In oncology, lineage addiction refers to the dependence of a tumor on master regulators of the normal tissue lineage it arose from, which act as survival oncogenes when amplified. This meaning comes from Garraway (2006) in Nature Reviews Cancer.[1]

Unit
Recovery means
Measured by

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Nearby constructs

dependence4 fields · 5 citationsjingle · one word, four constructs lineage3 fields · 7 citationsjingle · one word, three constructs master1 fields · 1 citationsanchor · a standalone construct

References

Garraway, L. A., & Sellers, W. R. (2006). Lineage dependency and lineage-survival oncogenes in human cancer. Nature Reviews Cancer, 6(8), 593-602. https://doi.org/10.1038/nrc1947

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