Construct · 1 fields · 1 citations

Lipinski's rule of five: a standalone construct

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Lipinski'srule of five1 CONSTRUCTLipinski's rule of fiveLIPINSKI · PHARMACOLOGY

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Pharmacology

guidelines on molecular weight, lipophilicity and hydrogen bonding that flag compounds likely to have poor oral absorption.

In pharmacology, Lipinski's rule of five refers to guidelines on molecular weight, lipophilicity and hydrogen bonding that flag compounds likely to have poor oral absorption. This meaning comes from Lipinski (1997) in Advanced Drug Delivery Reviews.[1]

Unit
Recovery means
Measured by

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Nearby constructs

absorption6 fields · 6 citationsjingle · one word, six constructsbeyond rule of five1 fields · 1 citationsanchor · a standalone constructdelivery1 fields · 1 citationsanchor · a standalone construct

References

  1. Lipinski, C. A., Lombardo, F., Dominy, B. W., & Feeney, P. J. (1997). Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Advanced Drug Delivery Reviews, 23(1-3), 3-25. https://doi.org/10.1016/s0169-409x(96)00423-1

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