Construct · 1 fields · 1 citations

model-informed precision dosing: a standalone construct

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model-informedprecision dosing1 CONSTRUCTModel-informed precisionDARWICH · PHARMACOMETRICS

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Pharmacometrics

dose individualization that combines population models with a patient's own data to predict the dose that reaches target exposure.

In pharmacometrics, model-informed precision dosing refers to dose individualization that combines population models with a patient's own data to predict the dose that reaches target exposure. This meaning comes from Darwich (2017) in Clinical Pharmacology & Therapeutics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

dose3 fields · 3 citationsinvariant · one construct, three systemsexposure6 fields · 13 citationsjingle · one name, six constructspopulation4 fields · 4 citationsjingle · one word, four constructs

References

  1. Darwich, A. S., Ogungbenro, K., Vinks, A. A., Powell, J. R., Reny, J., Marsousi, N., Daali, Y., Fairman, D., Cook, J., Lesko, L. J., McCune, J. S., Knibbe, C. A. J., de Wildt, S. N., Leeder, J. S., Neely, M., Zuppa, A. F., Vicini, P., Aarons, L., Johnson, T. N., Boiani, J., & Rostami‐Hodjegan, A. (2017). Why Has Model‐Informed Precision Dosing Not Yet Become Common Clinical Reality? Lessons From the Past and a Roadmap for the Future. Clinical Pharmacology & Therapeutics, 101(5), 646-656. https://doi.org/10.1002/cpt.659

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