Construct · 1 fields · 1 citations

Muller's ratchet: a standalone construct

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Population genetics

the irreversible build-up of harmful mutations in asexual populations because the least-loaded class is lost by chance and cannot be restored without recombination.

In population genetics, Muller's ratchet refers to the irreversible build-up of harmful mutations in asexual populations because the least-loaded class is lost by chance and cannot be restored without recombination. This meaning comes from Muller (1964) in Mutation Research.[1]

Unit
Recovery means
Measured by

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Nearby constructs

chance4 fields · 6 citationsjingle · one word, four constructs class3 fields · 3 citationsjingle · one word, three constructs mutation4 fields · 4 citationsjingle · one word, four constructs

References

Muller, H. J. (1964). The relation of recombination to mutational advance. Mutation Research, 1(1), 2-9. https://doi.org/10.1016/0027-5107(64)90047-8

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