Construct · 1 fields · 1 citations

noninferiority trial: a standalone construct

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Clinical research methods

a trial built to show that a new treatment is not worse than an active comparator by more than a prespecified margin.

In clinical research methods, noninferiority trial refers to a trial built to show that a new treatment is not worse than an active comparator by more than a prespecified margin. This meaning comes from Piaggio (2006) in JAMA.[1]

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Nearby constructs

margin2 fields · 2 citationsjingle · one word, two constructs treatment1 fields · 1 citationsanchor · a standalone construct

References

Piaggio, G., Elbourne, D. R., Altman, D. G., Pocock, S. J., Evans, S. J. W., & the CONSORT Group (2006). Reporting of Noninferiority and Equivalence Randomized Trials: An Extension of the CONSORT Statement. JAMA, 295(10), 1152. https://doi.org/10.1001/jama.295.10.1152

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