Construct · 1 fields · 1 citations

physiologically based pharmacokinetic model: a standalone construct

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Toxicokinetics

a model that represents the body as compartments with real organ volumes, blood flows and metabolic rates to predict tissue doses across species and routes.

In toxicokinetics, physiologically based pharmacokinetic model refers to a model that represents the body as compartments with real organ volumes, blood flows and metabolic rates to predict tissue doses across species and routes. This meaning comes from Ramsey (1984) in Toxicology and Applied Pharmacology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

body2 fields · 3 citationsjingle · one word, two constructs minimal physiologically based pharmacokinetic model1 fields · 1 citationsanchor · a standalone construct model3 fields · 3 citationsjingle · one word, three constructs

References

Ramsey, J. C., & Andersen, M. E. (1984). A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicology and Applied Pharmacology, 73(1), 159-175. https://doi.org/10.1016/0041-008x(84)90064-4

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