Construct · 1 fields · 1 citations

presenilin hypothesis: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
presenilinhypothesis1 CONSTRUCTPresenilin hypothesisSHEN · DEMENTIA RESEARCH

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Dementia research

the proposal that familial Alzheimer's disease mutations act mainly by reducing presenilin function, impairing memory and neuronal survival independently of amyloid beta accumulation.

In dementia research, presenilin hypothesis refers to the proposal that familial Alzheimer's disease mutations act mainly by reducing presenilin function, impairing memory and neuronal survival independently of amyloid beta accumulation. This meaning comes from Shen (2007) in Proceedings of the National Academy of Sciences.[1]

Unit
Recovery means
Measured by

Next

Run it through the Collider, or take the citations with you.

See how presenilin hypothesis sits against neighbouring constructs in the Collider, or export every reference on this page in one click.

Open in ColliderExport BibTeXReport this entry

Nearby constructs

accumulation3 fields · 3 citationsjingle · one word, three constructsbeta3 fields · 3 citationsjingle · one word, three constructsfunction5 fields · 6 citationsjingle · one word, five constructs

References

  1. Shen, J., & Kelleher, R. J. (2007). The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism. Proceedings of the National Academy of Sciences, 104(2), 403-409. https://doi.org/10.1073/pnas.0608332104

Cited on this page?

Confirm your construct, or correct us.

If your work is cited behind one of these entries, you know better than we do whether we captured the meaning right. Confirm it, suggest an edit, or dispute it, and your name goes on the entry as an author who has checked it, linked to your ORCID.

Claim your construct