Construct · 1 fields · 1 citations

promiscuous gene expression: a standalone construct

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Immunology

the display in thymic epithelium of genes from tissues throughout the body, letting developing T cells be screened against peripheral self.

In immunology, promiscuous gene expression refers to the display in thymic epithelium of genes from tissues throughout the body, letting developing T cells be screened against peripheral self. This meaning comes from Derbinski (2001) in Nature Immunology.[1]

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Nearby constructs

body2 fields · 3 citationsjingle · one word, two constructs display2 fields · 3 citationsjingle · one word, two constructs expression4 fields · 4 citationsjingle · one word, four constructs

References

Derbinski, J., Schulte, A., Kyewski, B., & Klein, L. (2001). Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nature Immunology, 2(11), 1032-1039. https://doi.org/10.1038/ni723

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