Construct · 1 fields · 1 citations

R-loop: a standalone construct

One name. One construct. A landmark on the map.

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Molecular biology

a three-stranded structure where nascent RNA pairs with template DNA and displaces the other strand, affecting transcription and genome stability.

In molecular biology, R-loop refers to a three-stranded structure where nascent RNA pairs with template DNA and displaces the other strand, affecting transcription and genome stability. This meaning comes from Skourti-Stathaki (2014) in Genes & Development.[1]

Unit
Recovery means
Measured by

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Nearby constructs

development1 fields · 2 citationsanchor · a standalone construct stability4 fields · 5 citationsjingle · one word, four constructs strand1 fields · 1 citationsanchor · a standalone construct

References

Skourti-Stathaki, K., & Proudfoot, N. J. (2014). A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression. Genes & Development, 28(13), 1384-1396. https://doi.org/10.1101/gad.242990.114

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