Construct · 1 fields · 1 citations

sign epistasis: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

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Evolutionary genetics

a form of gene interaction where a mutation is beneficial on some genetic backgrounds and harmful on others, constraining evolutionary paths.

In evolutionary genetics, sign epistasis refers to a form of gene interaction where a mutation is beneficial on some genetic backgrounds and harmful on others, constraining evolutionary paths. This meaning comes from Weinreich (2005) in Evolution.[1]

Unit
Recovery means
Measured by

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Nearby constructs

epistasis1 fields · 1 citationsanchor · a standalone construct form4 fields · 7 citationsjingle · one word, four constructs interaction3 fields · 7 citationsjingle · one word, three constructs

References

Weinreich, D. M., Watson, R. A., & Chao, L. (2005). Perspective: Sign Epistasis and Genetic Costraint on Evolutionary Trajectories. Evolution, 59(6), 1165-1174. https://doi.org/10.1111/j.0014-3820.2005.tb01768.x

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