Construct · 1 fields · 1 citations

size-independent ligand efficiency: a standalone construct

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size-independentligand efficiency1 CONSTRUCTSize-independent ligandNISSINK · MEDICINAL CHEMISTRY

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Medicinal chemistry

ligand efficiency rescaled by a fractional power of heavy atom count so that small and large ligands can be compared fairly.

In medicinal chemistry, size-independent ligand efficiency refers to ligand efficiency rescaled by a fractional power of heavy atom count so that small and large ligands can be compared fairly. This meaning comes from Nissink (2009) in Journal of Chemical Information and Modeling.[1]

Unit
Recovery means
Measured by

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count2 fields · 2 citationsjingle · one word, two constructsefficiency4 fields · 5 citationsjingle · one word, four constructsinformation4 fields · 5 citationsjingle · one word, four constructs

References

  1. Nissink, J. W. M. (2009). Simple Size-Independent Measure of Ligand Efficiency. Journal of Chemical Information and Modeling, 49(6), 1617-1622. https://doi.org/10.1021/ci900094m

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