Construct · 1 fields · 1 citations

tonic-phasic dopamine hypothesis: a standalone construct

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Biological psychiatry

the proposal that low tonic extracellular dopamine upregulates responsiveness to phasic dopamine release, with this balance disturbed in schizophrenia.

In biological psychiatry, tonic-phasic dopamine hypothesis refers to the proposal that low tonic extracellular dopamine upregulates responsiveness to phasic dopamine release, with this balance disturbed in schizophrenia. This meaning comes from Grace (1991) in Neuroscience.[1]

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tonic versus phasic dopamine1 fields · 1 citationsanchor · a standalone construct balance4 fields · 5 citationsjingle · one word, four constructs dopamine hypothesis of schizophrenia1 fields · 1 citationsanchor · a standalone construct

References

Grace, A. A. (1991). Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia. Neuroscience, 41(1), 1-24. https://doi.org/10.1016/0306-4522(91)90196-u

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