Construct · 1 fields · 1 citations

two-signal model of lymphocyte activation: a standalone construct

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two-signal model oflymphocyte activation1 CONSTRUCTTwo-signal model ofBRETSCHER · IMMUNOLOGY

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Immunology

the claim that a lymphocyte responds only when antigen recognition is joined by a second confirming signal.

In immunology, two-signal model of lymphocyte activation refers to the claim that a lymphocyte responds only when antigen recognition is joined by a second confirming signal. This meaning comes from Bretscher (1970) in Science.[1]

Unit
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Measured by

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Nearby constructs

two-signal model1 fields · 1 citationsanchor · a standalone constructself-nonself discrimination1 fields · 1 citationsanchor · a standalone constructactivation4 fields · 4 citationsjingle · one word, four constructs

References

  1. Bretscher, P., & Cohn, M. (1970). A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively. Science, 169(3950), 1042-1049. https://doi.org/10.1126/science.169.3950.1042

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