Construct · 1 fields · 1 citations

uncompetitive inhibition: a standalone construct

One name. One construct. A landmark on the map.

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uncompetitiveinhibition1 CONSTRUCTUncompetitive inhibitionCLELAND · ENZYMOLOGY

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Enzymology

reversible inhibition in which the inhibitor binds only the enzyme-substrate complex, lowering apparent Km and Vmax by the same factor.

In enzymology, uncompetitive inhibition refers to reversible inhibition in which the inhibitor binds only the enzyme-substrate complex, lowering apparent Km and Vmax by the same factor. This meaning comes from Cleland (1963) in Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects.[1]

Unit
Recovery means
Measured by

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Nearby constructs

Cleland notation1 fields · 1 citationsanchor · a standalone constructcompetitive inhibition1 fields · 1 citationsanchor · a standalone constructnoncompetitive inhibition1 fields · 1 citationsanchor · a standalone construct

References

  1. Cleland, W. W. (1963). The kinetics of enzyme-catalyzed reactions with two or more substrates or products. Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 67, 173-187. https://doi.org/10.1016/0926-6569(63)90226-8

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