Construct · 1 fields · 1 citations

beacon: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
beacon1 CONSTRUCTMolecular beaconTYAGI & KRAMER · 1996

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Molecular biology

A probe that lights up when it binds

In molecular biology a molecular beacon is a hairpin-shaped nucleic-acid probe carrying a fluorophore and a quencher at its ends, dark when closed but fluorescent when it hybridizes to its target sequence and springs open, separating the two. Tyagi and Kramer's 1996 paper introduced the design as a way to report the presence of a specific sequence in real time. The referent is a sequence-specific reporter probe that signals by fluorescence, unrelated to a radio marker or a WiFi frame beyond the shared idea of something that signals presence.[1]

Unit
The fluorescent signal emitted when the probe binds its target
Recovery means
Not applicable
Measured by
Measured by fluorescence intensity as a function of target hybridization

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Nearby constructs

bearing1 fields · 1 citationsanchor · a standalone constructclosed3 fields · 3 citationsjingle · one word, three constructs

References

  1. Tyagi, S., & Kramer, F. R. (1996). Molecular beacons: Probes that fluoresce upon hybridization. Nature Biotechnology, 14(3), 303–308. https://doi.org/10.1038/nbt0396-303

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