Construct · 1 fields · 1 citations

complement-mediated synapse elimination: a standalone construct

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complement-mediatedsynapse elimination1 CONSTRUCTComplement-mediatedSTEVENS · NEUROIMMUNOLOGY

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Neuroimmunology

the process by which complement proteins tag weak or unneeded synapses for removal by microglia during development, a mechanism also implicated in disease.

In neuroimmunology, complement-mediated synapse elimination refers to the process by which complement proteins tag weak or unneeded synapses for removal by microglia during development, a mechanism also implicated in disease. This meaning comes from Stevens (2007) in Cell.[1]

Unit
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Measured by

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructscomplement4 fields · 5 citationsjingle · one word, four constructsdevelopment1 fields · 2 citationsanchor · a standalone construct

References

  1. Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., Sher, A., Litke, A. M., Lambris, J. D., Smith, S. J., John, S. W. M., & Barres, B. A. (2007). The Classical Complement Cascade Mediates CNS Synapse Elimination. Cell, 131(6), 1164-1178. https://doi.org/10.1016/j.cell.2007.10.036

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