Construct · 3 fields · 3 citations
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In molecular biology, a duplex is a double-stranded stretch of nucleic acid in which two complementary strands are held together by base pairing, as in the DNA double helix or an annealed DNA–RNA pair. Watson and Crick's 1953 Molecular structure of nucleic acids: A structure for deoxyribose nucleic acid proposed the antiparallel double-helical pairing that is the archetypal duplex. The referent is a paired two-strand molecular structure, characterised by its melting temperature and the stability of its base pairing, and it has nothing in common with a two-way radio channel or a combined ultrasound scan beyond the Latin meaning of twofold.[1]
In vascular imaging, duplex refers to an ultrasound method that combines two modes in one instrument: a B-mode image of anatomy and a pulsed Doppler measurement of blood-flow velocity from a chosen site within that image. Barber and colleagues' 1974 Ultrasonic duplex echo-Doppler scanner described the instrument that merged the two, so an operator could place the flow sample precisely on the imaged vessel. The referent is the dual-mode imaging-plus-flow examination, assessed by flow velocities and vessel appearance, and it is a distinct construct from a paired DNA strand or a two-way communication link.[2]
In telecommunications, duplex describes a link that carries information in both directions: full-duplex sends and receives simultaneously (as on a telephone line), while half-duplex alternates direction (as on a walkie-talkie). Haykin's Communication systems treats the channel arrangements and the frequency- or time-division schemes that separate the two directions. The referent is the directionality arrangement of a communication channel, specified by whether and how both directions coexist, and it is unrelated to a nucleic-acid duplex or a dual-mode ultrasound beyond the shared idea of twofold.[3]
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