Construct · 2 fields · 2 citations

Where does hinge collide?

One name. Different field. Different construct. One map.

● jingle · one word, two constructs Nearest construct by meaning·not indexed
hinge2 CONSTRUCTSProtein hingeGERSTEIN · DOMAIN MOTIONFlexure hingeMENG · FLEXURE

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1994Protein hinge2013Flexure hinge
2026

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Structural biochemistry

a flexible protein segment about which rigid domains swing, letting the molecule open and close over a substrate.

In structural biochemistry, a hinge is a flexible segment of a protein about which rigid domains swing, letting the molecule open and close over a substrate or ligand as part of its function. Gerstein, Lesk, and Chothia's 1994 Structural Mechanisms for Domain Movements in Proteins classified these motions and the hinge and shear mechanisms that produce them. The referent is a localised region of conformational flexibility in a macromolecule, measured by the angle and axis of domain rotation, the same bending-joint metaphor as a rock fold or a machined flexure, but realised in a folded polypeptide.[1]

Unit
The angle and axis of domain rotation about the flexible segment
Recovery means
Not applicable
Measured by
Characterised by comparing open and closed structures and by normal-mode or molecular-dynamics analysis of domain motion

Precision engineering

A compliant joint that bends elastically

In precision mechanical engineering, a flexure hinge is a thin, compliant connection that allows limited, smooth rotation between two rigid parts by elastically bending rather than by sliding surfaces, so it moves without friction, backlash, or wear. Meng, Li, and Xu's 2013 New empirical stiffness equations for corner-filleted flexure hinges provides design formulas relating a hinge's geometry to its stiffness. The referent is an engineered compliant joint characterised by its rotational stiffness and range, carrying the same hinge image as a fold or a protein link but built deliberately into a mechanism.[2]

Unit
The rotational stiffness and allowable range of the compliant joint
Recovery means
Not applicable
Measured by
Determined from closed-form or finite-element stiffness equations and verified by load–deflection testing

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Nearby collisions

anagnorisis1 fields · 2 citationsanchor · a standalone constructaxis1 fields · 1 citationsanchor · a standalone constructbacklash2 fields · 2 citationsjingle · one word, two constructs

References

  1. Gerstein, M., Lesk, A. M., & Chothia, C. (1994). Structural mechanisms for domain movements in proteins. Biochemistry, 33(22), 6739–6749. https://doi.org/10.1021/bi00188a001
  2. Meng, Q., Li, Y., & Xu, J. (2013). New empirical stiffness equations for corner-filleted flexure hinges. Mechanical Sciences, 4(2), 345–356. https://doi.org/10.5194/ms-4-345-2013

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