Construct · 2 fields · 2 citations

Where does humoral collide?

One name. Different field. Different construct. One map.

● jingle · one word, two constructs Nearest construct by meaning·not indexed
humoral2 CONSTRUCTSHumoral regulationGROSSMAN · BLOOD-BORNEHumoral immunityANTIBODY · FLUID ARM

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1948Humoral regulation2006Humoral immunity
2026

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Physiology

Control carried by substances in the blood

In physiology, humoral means carried by the blood: humoral regulation is control exerted by chemical messengers released into the circulation, such as hormones, as opposed to direct nervous control, so a humoral mechanism acts at a distance through a blood-borne agent. Grossman, Robertson, and Ivy's 1948 Proof of a hormonal mechanism for gastric secretion demonstrated such humoral transmission of a stimulus. The referent is blood-borne chemical control, a construct that kept the old root meaning of fluid but sheds the four-humour theory, and it is separate from antibody-mediated immunity despite sharing the adjective.[1]

Unit
The blood-borne messenger mediating a regulatory effect
Recovery means
Not applicable
Measured by
Shown by transfer of an effect through blood or plasma and by messenger concentration

Immunology

Defence by antibodies in body fluids

In immunology, humoral immunity is the arm of adaptive defence mediated by antibodies and other soluble factors circulating in blood and lymph, as contrasted with cell-mediated immunity carried by T cells, the historic distinction between protection you can transfer with serum versus with cells. Casadevall and Pirofski's 2006 A reappraisal of humoral immunity based on mechanisms of antibody-mediated protection against intracellular pathogens revisits how this soluble-factor defence works. The referent is antibody-based, serum-transferable immunity, a construct distinct from the four-humour theory or blood-borne hormonal control, inheriting only the word's root meaning of the body's fluids.[2]

Unit
The soluble, serum-transferable component of the immune response
Recovery means
Not applicable
Measured by
Assessed by antibody titer and by protection transferable with serum rather than cells

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Nearby collisions

anamnesis2 fields · 2 citationsjingle · one word, two constructstemperament3 fields · 4 citationsjingle · one word, three constructsagent3 fields · 5 citationsjingle · one word, three constructshumor1 fields · 3 citationsanchor · a standalone construct

References

  1. Grossman, M. I., Robertson, C. R., & Ivy, A. C. (1948). Proof of a hormonal mechanism for gastric secretion: the humoral transmission of the distention stimulus. American Journal of Physiology-Legacy Content, 153(1), 1–9. https://doi.org/10.1152/ajplegacy.1948.153.1.1
  2. Casadevall, A., & Pirofski, L. (2006). A reappraisal of humoral immunity based on mechanisms of antibody-mediated protection against intracellular pathogens. In Advances in Immunology (pp. 1–44). Elsevier. https://doi.org/10.1016/s0065-2776(06)91001-3

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