Construct · 2 fields · 2 citations

Where does keyhole collide?

One name. Different field. Different construct. One map.

● jingle · one word, two constructs Nearest construct by meaning·not indexed
keyhole2 CONSTRUCTSKeyhole limpet hemocyaninHARRIS & MARKL · KLHKeyhole modeFABBRO · VAPOUR CHANNEL

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1999Keyhole limpet hemocyanin2010Keyhole mode
2026

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Immunology

A giant carrier protein from a marine snail

In immunology a keyhole refers to keyhole limpet hemocyanin (KLH), the large copper-bearing oxygen-transport protein of the marine mollusc Megathura crenulata, named for the keyhole-shaped aperture of the limpet's shell. Because it is so large, structurally foreign to mammals, and strongly immunogenic, KLH is used as a carrier to raise antibodies against small molecules and as an immune stimulant. Harris and Markl's 1999 review Keyhole limpet hemocyanin (KLH): A biomedical review surveys its structure and biomedical uses. The referent here is a specific protein and immunogen, sharing nothing with a welding cavity or a surgical approach but the limpet-shell image behind the word.[1]

Unit
The protein's molecular assembly and its immunogenic carrier activity
Recovery means
Not applicable
Measured by
Characterised by didecamer subunit structure, molecular mass, and antibody titres raised against KLH-conjugated antigens

Welding & joining

A vapour channel bored through the metal

In high-energy-density welding a keyhole is the narrow, vapour-filled channel that a laser or electron beam bores through the workpiece when its intensity is high enough to vaporise metal, letting the beam penetrate deeply while molten metal flows around the channel and solidifies behind it into a deep, narrow weld. Fabbro's 2010 Melt pool and keyhole behaviour analysis for deep penetration laser welding analyses how this channel forms and stays open. The referent is a transient cavity in a weld pool that enables deep-penetration welding, measured by penetration depth and stability, and it has nothing to do with a carrier protein or an operating-room approach beyond the keyhole image.[2]

Unit
The depth and stability of the vapour channel through the workpiece
Recovery means
Not applicable
Measured by
Tracked by penetration depth, keyhole stability and collapse, and the resulting weld aspect ratio

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Nearby collisions

aperture3 fields · 3 citationsjingle · one word, three constructsbeam1 fields · 2 citationsanchor · a standalone constructcarrier3 fields · 3 citationsjingle · one word, three constructs

References

  1. Harris, J., & Markl, J. (1999). Keyhole limpet hemocyanin (KLH): A biomedical review. Micron, 30(6), 597–623. https://doi.org/10.1016/s0968-4328(99)00036-0
  2. Fabbro, R. (2010). Melt pool and keyhole behaviour analysis for deep penetration laser welding. Journal of Physics D: Applied Physics, 43(44), 445501. https://doi.org/10.1088/0022-3727/43/44/445501

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