Construct · 1 fields · 1 citations

plasmid: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a single construct Nearest construct by meaning·not indexed
plasmid1 CONSTRUCTPlasmidLEDERBERG · 1952

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Molecular biology

DNA that replicates apart from the chromosome

In molecular biology, a plasmid is a small DNA molecule, usually circular, that replicates independently of the host chromosome and can carry accessory genes such as those for antibiotic resistance. Lederberg's 1952 Cell genetics and hereditary symbiosis introduced the word plasmid as a general term for extrachromosomal hereditary determinants. The referent is an autonomous, self-replicating genetic element distinct from the main genome, characterised by its copy number, replication origin, and the traits it confers, and it later became the standard vehicle for carrying DNA in genetic engineering.[1]

Unit
The copy number and gene content of the independently replicating element
Recovery means
Not applicable
Measured by
Characterised by copy number, size, replication origin, and the phenotypes (such as resistance) the carried genes confer

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Nearby constructs

carry1 fields · 1 citationsanchor · a standalone constructcell2 fields · 3 citationsjingle · one word, two constructsclone3 fields · 3 citationsjingle · one word, three constructs

References

  1. Lederberg, J. (1952). Cell genetics and hereditary symbiosis. Physiological Reviews, 32(4), 403–430. https://doi.org/10.1152/physrev.1952.32.4.403

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