Construct · 2 fields · 2 citations

crosstalk: one construct, many systems

One name. One construct. Different systems. One map.

● invariant · one construct, two systems Nearest construct by meaning·not indexed
term borrowed from signal lines to signaling pathwayscrosstalk2 SYSTEMSSignal crosstalkJOHNSON & GRAHAM · COUPLINGPathway cross-talkGUO & WANG · PATHWAYS

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1993Signal crosstalk2009Pathway cross-talk
2026

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Electronics

Signal on one line leaks into another

In electronics and telecommunications, crosstalk is the unwanted transfer of a signal from one circuit or channel into a neighbouring one through capacitive or inductive coupling, so that activity on an aggressor line appears as interference on a victim line that should have been independent. Johnson and Graham's High-Speed Digital Design: A Handbook of Black Magic treats how trace spacing, return paths, and edge rates set the coupled noise. The referent is interference between nominally separate channels, quantified as coupled voltage or a coupling ratio. It is the same construct that biologists later borrowed to describe interacting signaling pathways.[1]

Unit
The coupled signal in the victim channel (e.g., near/far-end crosstalk ratio)
Recovery means
Not applicable
Measured by
Quantified by near-end and far-end crosstalk ratios, coupled-noise amplitude, and channel-to-channel isolation

Cell biology

One signaling pathway influences another

In cell biology, cross-talk is the interaction between distinct signal-transduction pathways, where a component of one pathway modifies the activity or output of another, so that pathways treated as separate in fact influence one another's response. Guo and Wang's 2009 Signaling cross-talk between TGF-β/BMP and other pathways reviews how shared mediators and feedback let these cascades converge and modulate each other. It is the same abstract construct as electronic crosstalk (interaction leaking between channels meant to be independent), realised in a molecular signaling network rather than a wiring harness, and read out through pathway activity rather than coupled voltage.[2]

Unit
The change in one pathway's activity caused by another
Recovery means
Not applicable
Measured by
Shown by perturbing one pathway and reading changes in another's reporters, phosphorylation, or target-gene expression

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Nearby constructs

coupling4 fields · 4 citationsjingle · one word, four constructscell2 fields · 3 citationsjingle · one word, two constructschannel4 fields · 4 citationsjingle · one word, four constructs

References

  1. Johnson, H. W., & Graham, M. (1993). High-speed digital design: A handbook of black magic. Prentice Hall. ISBN 9780133957242
  2. Guo, X., & Wang, X.-F. (2009). Signaling cross-talk between TGF-β/BMP and other pathways. Cell Research, 19(1), 71–88. https://doi.org/10.1038/cr.2008.302

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