Construct · 2 fields · 3 citations

Where does dogma collide?

One name. Different field. Different construct. One map.

● jingle · one word, two constructs Nearest construct by meaningcentral dogma of molecular biologycompare the meanings
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dogma2 CONSTRUCTSPhilosophical dogmaQUINE · TWO DOGMASCentral dogmaCRICK · DNA TO PROTEIN

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2026

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Philosophy

An unexamined presupposition of a theory

In philosophy, a dogma in this critical usage is a presupposition that a theory or school takes for granted without adequate justification. Quine's 1951 paper Two Dogmas of Empiricism gave this framing its modern statement by naming two such assumptions of the empiricism of his day, the sharp analytic-synthetic distinction and reductionism, and arguing that both were unearned. The pejorative use of the word is older, reaching back through Kant's critique of dogmatism to the ancient skeptics who set themselves against the dogmatists, but Quine supplied the analytic account of a dogma as a hidden, load-bearing assumption. The referent is a belief a thinker holds uncritically and then targets for examination, not a defined article of religious faith nor a principle of molecular biology.[1]

Unit
One presupposition a theory holds without justification
Recovery means
Not applicable
Measured by
Exposed by philosophical analysis that reconstructs an argument and identifies its unearned premises

Molecular biology

Information flows DNA to RNA to protein

In molecular biology, the central dogma states that detailed sequence information passes from nucleic acid to protein and cannot pass back out of protein into nucleic acid or protein. Crick introduced the term in his 1958 lecture On Protein Synthesis and restated it precisely in his 1970 paper Central Dogma of Molecular Biology, clarifying that it concerns the one-way transfer of sequence information, commonly summarised as DNA to RNA to protein. It is a claim about what the cell's molecular machinery can and cannot do, and it is settled or revised by experiment rather than by authority. The referent is a rule about the direction of genetic information, not a truth revealed to a faith community nor an assumption a philosopher aims to unsettle.[2][3]

Unit
One directional constraint on how sequence information transfers among DNA, RNA, and protein
Recovery means
Not applicable
Measured by
Tested experimentally by tracing whether sequence information moves in a given direction, as in transcription, translation, and reverse transcription

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Nearby collisions

belief4 fields · 4 citationsjingle · one word, four constructsparadigm3 fields · 4 citationsjingle · one word, three constructscanon3 fields · 3 citationsjingle · one word, three constructs

References

  1. Quine, W. V. (1951). Two dogmas of empiricism. The Philosophical Review, 60(1), 20–43. https://doi.org/10.2307/2181906
  2. Crick, F. H. C. (1958). On protein synthesis. Symposia of the Society for Experimental Biology, 12, 138–163.
  3. Crick, F. (1970). Central dogma of molecular biology. Nature, 227(5258), 561–563. https://doi.org/10.1038/227561a0

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