Construct · 2 fields · 2 citations
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In molecular genetics, slippage (slipped-strand mispairing) happens when DNA is being copied through a short repeated sequence and the two strands briefly detach and re-pair out of register, so the polymerase adds or drops a repeat unit. Repeated over generations this is a main engine behind the expansion and contraction of microsatellites and other tandem repeats, and behind some repeat-expansion diseases. Levinson and Gutman set it out as a general mechanism of DNA sequence evolution. The referent is a copying error at the molecular scale, with no connection to trading losses beyond the shared word for slipping.[1]
In finance, slippage is the difference between the price a trader expected when deciding to trade and the price actually achieved once the order reaches the market, caused by delay, price movement, and the market impact of the order itself. On a large order worked over time it is the main hidden cost of execution, and reducing it is the goal of trade scheduling and execution algorithms. Perold framed this gap as the implementation shortfall, the distance between a paper portfolio and the real one. The referent is an execution cost in a market, unrelated to a DNA copying error.[2]
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